Correlation between increased atrial expression of genes related to fatty acid metabolism and autophagy in patients with chronic atrial fibrillation

Yasushige Shingu; Shingo Takada; Takashi Yokota; Ryosuke Shirakawa; Akira Yamada; Tomonori Ooka; Hiroki Katoh; Suguru Kubota; Yoshiro Matsui

doi:10.1371/journal.pone.0224713

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Open Access

Peer-reviewed

Research Article

Correlation between increased atrial expression of genes related to fatty acid metabolism and autophagy in patients with chronic atrial fibrillation

Yasushige Shingu,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Writing – original draft

Affiliation Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
⨯
Shingo Takada,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan

http://orcid.org/0000-0002-7781-9482

⨯
Takashi Yokota ,

Roles Conceptualization, Data curation, Funding acquisition, Writing – original draft

* E-mail: t-yokota@med.hokudai.ac.jp

Affiliation Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan

http://orcid.org/0000-0001-5470-6648

⨯
Ryosuke Shirakawa,

Roles Investigation, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
⨯
Akira Yamada,

Roles Investigation, Writing – review & editing

Affiliation Department of Cardiovascular Surgery, Teine Keijinkai Hospital, Sapporo, Japan
⨯
Tomonori Ooka,

Roles Investigation, Writing – review & editing

Affiliation Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
⨯
Hiroki Katoh,

Roles Investigation, Writing – review & editing

Affiliation Emergency and Critical Care Center, Hokkaido University Hospital, Sapporo, Japan
⨯
Suguru Kubota,

Roles Investigation, Writing – review & editing

Affiliation Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
⨯
Yoshiro Matsui

Roles Conceptualization, Investigation, Supervision, Writing – review & editing

Affiliation Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
⨯

Correlation between increased atrial expression of genes related to fatty acid metabolism and autophagy in patients with chronic atrial fibrillation

Yasushige Shingu,
Shingo Takada,
Takashi Yokota,
Ryosuke Shirakawa,
Akira Yamada,
Tomonori Ooka,
Hiroki Katoh,
Suguru Kubota,
Yoshiro Matsui

Published: April 21, 2020
https://doi.org/10.1371/journal.pone.0224713
See the preprint

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Fatty acids
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Atrial fibrillation
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Gene expression
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Autophagic cell death
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Cardiac atria
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Mitochondria
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Protein expression
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Myocardium
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