Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging

• Chenguang Zhou ,

  Contributed equally to this work with: Chenguang Zhou, Hao Cai

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Current address: Boxer Capital, Tavistock Group, San Diego, California, United States of America

  Affiliation Research and Early Development, Genentech Inc., South San Francisco, California, United States of America

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• Hao Cai ,

  Contributed equally to this work with: Chenguang Zhou, Hao Cai

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Research and Early Development, Genentech Inc., South San Francisco, California, United States of America

  http://orcid.org/0000-0002-4937-085X

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• Amos Baruch,

  Roles Conceptualization, Writing – review & editing

  Affiliation Research and Early Development, Genentech Inc., South San Francisco, California, United States of America

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• Nicholas Lewin-Koh,

  Roles Formal analysis, Writing – review & editing

  Affiliation Product Development, Genentech Inc., South San Francisco, California, United States of America

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• Meng Yang,

  Roles Methodology

  Affiliation WuXi AppTec (Shanghai) Co., Ltd., Shanghai, China

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• Fengxun Guo,

  Roles Methodology

  Affiliation WuXi AppTec (Shanghai) Co., Ltd., Shanghai, China

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• Deming Xu,

  Roles Methodology, Supervision

  Affiliation WuXi AppTec (Shanghai) Co., Ltd., Shanghai, China

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• Rong Deng,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Research and Early Development, Genentech Inc., South San Francisco, California, United States of America

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• Wouter Hazenbos,

  Roles Conceptualization, Writing – review & editing

  Affiliation Research and Early Development, Genentech Inc., South San Francisco, California, United States of America

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• Amrita V. Kamath

  Roles Conceptualization, Supervision, Writing – review & editing

  * E-mail: kamath.amrita@gene.com

  Affiliation Research and Early Development, Genentech Inc., South San Francisco, California, United States of America

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