Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study

Ira Dicker; Sharon Zhang; Neelanjana Ray; Brett R. Beno; Alicia Regueiro-Ren; Samit Joshi; Mark Cockett; Mark Krystal; Max Lataillade

doi:10.1371/journal.pone.0224076

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Open Access

Peer-reviewed

Research Article

Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study

Ira Dicker,

Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of HIV Discovery, ViiV Healthcare, Branford, Connecticut, United States of America
⨯
Sharon Zhang,

Roles Investigation

Affiliation Department of HIV Discovery, ViiV Healthcare, Branford, Connecticut, United States of America
⨯
Neelanjana Ray,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Department of Early Development, Bristol-Myers Squibb Research and Development, Princeton, New Jersey, United States of America
⨯
Brett R. Beno,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Department of Molecular Discovery Technologies, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America
⨯
Alicia Regueiro-Ren,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Chemistry Bristol-Myers Squibb Research and Development, Wallingford Connecticut, United States of America

http://orcid.org/0000-0003-2991-719X

⨯
Samit Joshi,

Roles Conceptualization, Investigation, Methodology, Writing – review & editing

Affiliation Department of Early Development, ViiV Healthcare, Branford, Connecticut, United States of America
⨯
Mark Cockett,

Roles Supervision, Writing – review & editing

Affiliation Department of HIV Discovery, ViiV Healthcare, Branford, Connecticut, United States of America
⨯
Mark Krystal ,

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

* E-mail: Mark.R.Krystal@viivhealthcare.com

Affiliation Department of HIV Discovery, ViiV Healthcare, Branford, Connecticut, United States of America

http://orcid.org/0000-0001-8905-2584

⨯
Max Lataillade

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Department of Early Development, ViiV Healthcare, Branford, Connecticut, United States of America
⨯

Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study

Ira Dicker,
Sharon Zhang,
Neelanjana Ray,
Brett R. Beno,
Alicia Regueiro-Ren,
Samit Joshi,
Mark Cockett,
Mark Krystal,
Max Lataillade

Published: October 17, 2019
https://doi.org/10.1371/journal.pone.0224076

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