Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses

• Lucia Vojtech ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: luciav@uw.edu (LV); fhladik@fredhutch.org (FH)

  Affiliation Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America

  http://orcid.org/0000-0003-2343-0719

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• Mengying Zhang,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Molecular Engineering and Sciences Institute, University of Washington, Seattle, Washington, United States of America

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• Veronica Davé,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America

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• Claire Levy,

  Roles Data curation, Investigation

  Affiliation Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America

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• Sean M. Hughes,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America

  http://orcid.org/0000-0002-9409-9405

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• Ruofan Wang,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America

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• Fernanda Calienes,

  Roles Investigation, Validation

  Affiliation Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America

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• Martin Prlic,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America, Department of Immunology, University of Washington, Seattle, Washington, United States of America

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• Elizabeth Nance,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Molecular Engineering and Sciences Institute, University of Washington, Seattle, Washington, United States of America, Department of Chemical Engineering, University of Washington, Seattle, Washington, United States of America

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• Florian Hladik

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: luciav@uw.edu (LV); fhladik@fredhutch.org (FH)

  Affiliations Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, United States of America

  http://orcid.org/0000-0002-0375-2764

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