Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP

Katsuya Narumi; Tsukika Ohata; Yuichi Horiuchi; Hiroshi Satoh; Ayako Furugen; Masaki Kobayashi; Ken Iseki

doi:10.1371/journal.pone.0223892

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Peer-reviewed

Research Article

Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP

Katsuya Narumi ,

Contributed equally to this work with: Katsuya Narumi, Tsukika Ohata

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Writing – original draft

Affiliation Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Tsukika Ohata ,

Contributed equally to this work with: Katsuya Narumi, Tsukika Ohata

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Yuichi Horiuchi,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Hiroshi Satoh,

Roles Methodology, Writing – review & editing

Affiliation Research and Development Division, Hokkaido Research Institute, Nissei Bio Co. Ltd, Eniwa, Hokkaido, Japan
⨯
Ayako Furugen,

Roles Writing – review & editing

Affiliation Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Masaki Kobayashi ,

Roles Conceptualization, Project administration, Writing – review & editing

* E-mail: masaki@pharm.hokudai.ac.jp (MK); ken-i@pharm.hokudai.ac.jp (KI)

Affiliation Department of Pharmacy, Hokkaido University Hospital, Sapporo, Hokkaido, Japan
⨯
Ken Iseki

Roles Conceptualization, Project administration, Writing – review & editing

* E-mail: masaki@pharm.hokudai.ac.jp (MK); ken-i@pharm.hokudai.ac.jp (KI)

Affiliations Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan, Department of Pharmacy, Hokkaido University Hospital, Sapporo, Hokkaido, Japan

http://orcid.org/0000-0003-4018-7298

⨯

Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP

Katsuya Narumi,
Tsukika Ohata,
Yuichi Horiuchi,
Hiroshi Satoh,
Ayako Furugen,
Masaki Kobayashi,
Ken Iseki

Published: October 21, 2019
https://doi.org/10.1371/journal.pone.0223892

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Nucleosides
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Caco-2 cells
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Gastrointestinal tract
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