Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

Arjan Mofers; Paola Perego; Karthik Selvaraju; Laura Gatti; Joachim Gullbo; Stig Linder; Padraig D'Arcy

doi:10.1371/journal.pone.0223807

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Open Access

Peer-reviewed

Research Article

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

Arjan Mofers,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

Affiliation Department of Medicine and Health, Linköping University, Linköping, Sweden

http://orcid.org/0000-0001-9972-2086

⨯
Paola Perego,

Roles Conceptualization, Formal analysis, Supervision, Validation, Visualization, Writing – original draft

Affiliation Molecular Pharmacology Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
⨯
Karthik Selvaraju,

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft

Affiliation Department of Medicine and Health, Linköping University, Linköping, Sweden
⨯
Laura Gatti,

Roles Formal analysis, Investigation, Visualization, Writing – original draft

Affiliation Cerebrovascular Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy

http://orcid.org/0000-0001-6751-5031

⨯
Joachim Gullbo,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft

Affiliation Department of Radiology, Oncology and Radiation Science, Section of Oncology, Uppsala University, Uppsala, Sweden
⨯
Stig Linder,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Visualization, Writing – original draft

Affiliations Department of Medicine and Health, Linköping University, Linköping, Sweden, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
⨯
Padraig D'Arcy

Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft

* E-mail: padraig.darcy@liu.se

Affiliation Department of Medicine and Health, Linköping University, Linköping, Sweden
⨯

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

Arjan Mofers,
Paola Perego,
Karthik Selvaraju,
Laura Gatti,
Joachim Gullbo,
Stig Linder,
Padraig D'Arcy

Published: October 22, 2019
https://doi.org/10.1371/journal.pone.0223807

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