Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease

• Jonathan Mauricio Muñoz-Cabrera ,

  Contributed equally to this work with: Jonathan Mauricio Muñoz-Cabrera, Adrián Gabriel Sandoval-Hernández

  Roles Formal analysis, Investigation

  Affiliation Behavioral Neurophysiology Laboratory, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

  http://orcid.org/0000-0003-2964-0573

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• Adrián Gabriel Sandoval-Hernández ,

  Contributed equally to this work with: Jonathan Mauricio Muñoz-Cabrera, Adrián Gabriel Sandoval-Hernández

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft

  * E-mail: agsandovalh@unal.edu.co (AGSH); famunerag@unal.edu.co (AM); gharboledab@unal.edu.co (GA)

  Affiliation Grupo de Muerte Celular, Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia

  http://orcid.org/0000-0002-0661-6872

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• Andrea Niño,

  Roles Investigation

  Affiliation Grupo de Muerte Celular, Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia

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• Tatiana Báez,

  Roles Investigation

  Affiliation Grupo de Muerte Celular, Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia

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• Angie Bustos-Rangel,

  Roles Investigation

  Affiliation Grupo de Muerte Celular, Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia

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• Gloria Patricia Cardona-Gómez,

  Roles Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Área de Neurobiología Celular y Molecular, Grupo de Neurociencias de Antioquia, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia

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• Alejandro Múnera ,

  Roles Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – original draft

  * E-mail: agsandovalh@unal.edu.co (AGSH); famunerag@unal.edu.co (AM); gharboledab@unal.edu.co (GA)

  Affiliation Behavioral Neurophysiology Laboratory, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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• Gonzalo Arboleda

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft

  * E-mail: agsandovalh@unal.edu.co (AGSH); famunerag@unal.edu.co (AM); gharboledab@unal.edu.co (GA)

  Affiliation Grupo de Muerte Celular, Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia

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