Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1

Yi Zuo; J. Charles Whitbeck; Gabriel J. Haila; Abraham A. Hakim; Paul W. Rothlauf; Roselyn J. Eisenberg; Gary H. Cohen; Claude Krummenacher

doi:10.1371/journal.pone.0223299

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Open Access

Peer-reviewed

Research Article

Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1

Yi Zuo †,

Contributed equally to this work with: Yi Zuo, J. Charles Whitbeck

† Deceased.

Roles Conceptualization, Investigation, Methodology

Affiliation Department of Microbiology, School of Dental Medicine University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
J. Charles Whitbeck ,

Contributed equally to this work with: Yi Zuo, J. Charles Whitbeck

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Microbiology, School of Dental Medicine University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Gabriel J. Haila,

Roles Investigation, Writing – review & editing

Affiliation Department of Chemistry and Biochemistry, Rowan University, Glassboro, New Jersey, United States of America
⨯
Abraham A. Hakim,

Roles Investigation, Writing – review & editing

Affiliation Department of Biological Sciences, Rowan University, Glassboro, New Jersey, United States of America
⨯
Paul W. Rothlauf,

Roles Investigation, Writing – review & editing

Affiliation Department of Biological Sciences, Rowan University, Glassboro, New Jersey, United States of America
⨯
Roselyn J. Eisenberg,

Roles Conceptualization, Resources, Supervision, Writing – review & editing

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Gary H. Cohen,

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

Affiliation Department of Microbiology, School of Dental Medicine University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Claude Krummenacher

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Krummenacher@rowan.edu

Affiliations Department of Biological Sciences, Rowan University, Glassboro, New Jersey, United States of America, Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, New Jersey, United States of America

http://orcid.org/0000-0002-3492-4987

⨯

Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1

Yi Zuo,
J. Charles Whitbeck,
Gabriel J. Haila,
Abraham A. Hakim,
Paul W. Rothlauf,
Roselyn J. Eisenberg,
Gary H. Cohen,
Claude Krummenacher

Published: October 3, 2019
https://doi.org/10.1371/journal.pone.0223299

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Saliva
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Herpes simplex virus-1
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Fibroblasts
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Antibodies
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Viral pathogens
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Herpes simplex virus-2
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Herpesviruses
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Medical risk factors
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