Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors

Lili Wang; Yunqian Li; Ran Guo; Shanshan Li; Anqi Chang; Zhixiang Zhu; Pengfei Tu

doi:10.1371/journal.pone.0223096

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Open Access

Peer-reviewed

Research Article

Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors

Lili Wang,

Roles Investigation, Methodology

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
⨯
Yunqian Li,

Roles Investigation, Methodology

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
⨯
Ran Guo,

Roles Methodology

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
⨯
Shanshan Li,

Roles Methodology

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
⨯
Anqi Chang,

Roles Investigation

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
⨯
Zhixiang Zhu ,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Writing – original draft

* E-mail: ahssfxgt@163.com (ZZ); pengfeitu@163.com (PT)

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China

http://orcid.org/0000-0002-7476-309X

⨯
Pengfei Tu

Roles Supervision

* E-mail: ahssfxgt@163.com (ZZ); pengfeitu@163.com (PT)

Affiliation Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
⨯

Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors

Lili Wang,
Yunqian Li,
Ran Guo,
Shanshan Li,
Anqi Chang,
Zhixiang Zhu,
Pengfei Tu

Published: October 10, 2019
https://doi.org/10.1371/journal.pone.0223096

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Bioluminescence
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Platelet activation
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