Optimising poly(lactic-co-glycolic acid) microparticle fabrication using a Taguchi orthogonal array design-of-experiment approach

R. A. Mensah; S. B. Kirton; M. T. Cook; I. D. Styliari; V. Hutter; D. Y. S. Chau

doi:10.1371/journal.pone.0222858

Loading metrics

Open Access

Peer-reviewed

Research Article

Optimising poly(lactic-co-glycolic acid) microparticle fabrication using a Taguchi orthogonal array design-of-experiment approach

R. A. Mensah,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, England, United Kingdom, Department of Biomaterials and Tissue Engineering, Eastman Dental Institute, UCL, London, England, United Kingdom
⨯
S. B. Kirton,

Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – review & editing

Affiliation Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, England, United Kingdom
⨯
M. T. Cook,

Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – review & editing

Affiliation Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, England, United Kingdom
⨯
I. D. Styliari,

Roles Data curation, Formal analysis, Supervision, Writing – review & editing

Affiliation Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, England, United Kingdom
⨯
V. Hutter,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Supervision, Writing – review & editing

Affiliation Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, England, United Kingdom
⨯
D. Y. S. Chau

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: d.chau@ucl.ac.uk

Affiliations Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, England, United Kingdom, Department of Biomaterials and Tissue Engineering, Eastman Dental Institute, UCL, London, England, United Kingdom

http://orcid.org/0000-0001-9200-6749

⨯

Optimising poly(lactic-co-glycolic acid) microparticle fabrication using a Taguchi orthogonal array design-of-experiment approach

R. A. Mensah,
S. B. Kirton,
M. T. Cook,
I. D. Styliari,
V. Hutter,
D. Y. S. Chau

Published: September 26, 2019
https://doi.org/10.1371/journal.pone.0222858

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Emulsions
Is the Subject Area "Emulsions" applicable to this article?

Thanks for your feedback.
Evaporation
Is the Subject Area "Evaporation" applicable to this article?

Thanks for your feedback.
Solvents
Is the Subject Area "Solvents" applicable to this article?

Thanks for your feedback.
Polymers
Is the Subject Area "Polymers" applicable to this article?

Thanks for your feedback.
Drug delivery
Is the Subject Area "Drug delivery" applicable to this article?

Thanks for your feedback.
Computer software
Is the Subject Area "Computer software" applicable to this article?

Thanks for your feedback.
Experimental design
Is the Subject Area "Experimental design" applicable to this article?

Thanks for your feedback.
Scanning electron microscopy
Is the Subject Area "Scanning electron microscopy" applicable to this article?

Thanks for your feedback.