Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function

Evan Yang; Christina Mundy; Eric F. Rappaport; Maurizio Pacifici; Paul C. Billings

doi:10.1371/journal.pone.0222784

Loading metrics

Open Access

Peer-reviewed

Research Article

Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function

Evan Yang,

Roles Data curation, Software, Writing – review & editing

Current address: Graduate Program in Biological and Biomedical Sciences (BBS), Harvard Medical School, Boston, Massachusetts, United States of America

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Christina Mundy,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Eric F. Rappaport,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Molecular Genetics Core, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Maurizio Pacifici,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
⨯
Paul C. Billings

Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

* E-mail: BillingsP@email.chop.edu

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

http://orcid.org/0000-0002-1365-7664

⨯

Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function

Evan Yang,
Christina Mundy,
Eric F. Rappaport,
Maurizio Pacifici,
Paul C. Billings

Published: September 19, 2019
https://doi.org/10.1371/journal.pone.0222784

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Protein structure prediction
Is the Subject Area "Protein structure prediction" applicable to this article?

Thanks for your feedback.
Extracellular matrix proteins
Is the Subject Area "Extracellular matrix proteins" applicable to this article?

Thanks for your feedback.
Heparin
Is the Subject Area "Heparin" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.
Protein domains
Is the Subject Area "Protein domains" applicable to this article?

Thanks for your feedback.
Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.