Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis

• Javier Lozano-Gerona,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Instituto Aragonés de Ciencias de la Salud (IACS) y Instituto de Investigación Sanitaria (IIS) Aragón, Zaragoza, Spain

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• Aida Oliván-Viguera,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Biosignal Interpretation and Computational Simulation (BSICoS), Aragón Institute of Engineering Research (I3A), Univ. of Zaragoza, Zaragoza, Spain

  http://orcid.org/0000-0001-5348-924X

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• Pablo Delgado-Wicke,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Departamento de Biología, Facultad de Ciencias, UAM, Madrid, Spain

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• Vikrant Singh,

  Roles Investigation, Writing – review & editing

  Affiliation Dept. of Pharmacology, University of California, Davis, CA, United States of America

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• Brandon M. Brown,

  Roles Investigation, Writing – review & editing

  Affiliation Dept. of Pharmacology, University of California, Davis, CA, United States of America

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• Elena Tapia-Casellas,

  Roles Investigation, Methodology, Resources, Visualization, Writing – review & editing

  Affiliation Scientific and Technical Service, Aragónese Center for Biomedical Research, Univ. of Zaragoza, Zaragoza, Spain

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• Esther Pueyo,

  Roles Funding acquisition, Methodology, Resources, Writing – review & editing

  Affiliation Biosignal Interpretation and Computational Simulation (BSICoS), Aragón Institute of Engineering Research (I3A), Univ. of Zaragoza, Zaragoza, Spain

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• Marta Sofía Valero,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Dept. of Pharmacology and Physiology, Univ. of Zaragoza, Huesca, Spain

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• Ángel-Luis Garcia-Otín,

  Roles Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Instituto Aragonés de Ciencias de la Salud (IACS) y Instituto de Investigación Sanitaria (IIS) Aragón, Zaragoza, Spain

  http://orcid.org/0000-0002-5123-2480

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• Pilar Giraldo,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Spanish Foundation for the Study and Treatment of Gaucher Disease and other Lysosomal Disorders (FEETEG), Zaragoza, Spain

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• Edgar Abarca-Lachen,

  Roles Investigation, Writing – review & editing

  Affiliation Universidad San Jorge, Faculty of Health Sciences, Villanueva de Gállego, Spain

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• Joaquín C. Surra,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Departamento de Producción Animal y Ciencia de los Alimentos, CIBER-obn, Univ. of Zaragoza, Zaragoza, Spain

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• Jesús Osada,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Departamento Bioquímica y Biología Molecular y Celular (CIBEROBN), Facultad de Veterinaria, Univ. of Zaragoza, Zaragoza, Spain

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• Kirk L. Hamilton,

  Roles Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Dept. of Physiology, School of Biomedical Sciences, Univ. of Otago, Dunedin, New Zealand

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• Siba P. Raychaudhuri,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Medicine and Dermatology, School of Medicine UC Davis and VA Sacramento Medical Center University of California, Mather, California, United States of America

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• Miguel Marigil,

  Roles Investigation, Methodology, Resources, Visualization, Writing – review & editing

  Affiliation Dept. of Pathology, Hospital San Jorge, Huesca, Spain

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• Ángeles Juarranz,

  Roles Investigation, Methodology, Resources, Visualization, Writing – review & editing

  Affiliations Departamento de Biología, Facultad de Ciencias, UAM, Madrid, Spain, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Madrid, Spain

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• Heike Wulff,

  Roles Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Dept. of Pharmacology, University of California, Davis, CA, United States of America

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• Hiroto Miura,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Dept. of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, United States of America

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• Yolanda Gilaberte,

  Roles Conceptualization, Investigation, Resources, Writing – review & editing

  Affiliation Dept. of Dermatology, Univ. Hospital Miguel Servet, IIS Aragón, Zaragoza, Spain

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•  [ ... ],
• Ralf Köhler

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kohler@araid.es

  Affiliations Instituto Aragonés de Ciencias de la Salud (IACS) y Instituto de Investigación Sanitaria (IIS) Aragón, Zaragoza, Spain, Aragón Agency for Research and Development (ARAID), Zaragoza, Spain

  http://orcid.org/0000-0001-9563-2913

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