Structural characterization of the saxitoxin-targeting APTSTX1 aptamer using optical tweezers and molecular dynamics simulations

• Nathalie Casanova-Morales ,

  Contributed equally to this work with: Nathalie Casanova-Morales, Nataniel L. Figueroa, Karol Alfaro, Felipe Montenegro

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Instituto de Física, Pontificia Universidad Católica de Chile, Santiago, Chile, Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile, Facultad de Artes Liberales, Universidad Adolfo Ibáñez, Santiago, Chile

  http://orcid.org/0000-0002-9706-0952

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• Nataniel L. Figueroa ,

  Contributed equally to this work with: Nathalie Casanova-Morales, Nataniel L. Figueroa, Karol Alfaro, Felipe Montenegro

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Instituto de Física, Pontificia Universidad Católica de Chile, Santiago, Chile

  http://orcid.org/0000-0001-7703-1129

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• Karol Alfaro ,

  Contributed equally to this work with: Nathalie Casanova-Morales, Nataniel L. Figueroa, Karol Alfaro, Felipe Montenegro

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation CIGREN. Instituto de Biología. Facultad de Ciencias. Universidad de Valparaíso, Valparaíso, Chile

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• Felipe Montenegro ,

  Contributed equally to this work with: Nathalie Casanova-Morales, Nataniel L. Figueroa, Karol Alfaro, Felipe Montenegro

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile

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• Nelson P. Barrera ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: nbarrera@bio.puc.cl (NPB); jmaze@fis.puc.cl (JRM); yitowilson@gmail.com (CAMW); pablo.conejeros@uv.cl (PC)

  Affiliation Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile

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• J. R. Maze ,

  Roles Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: nbarrera@bio.puc.cl (NPB); jmaze@fis.puc.cl (JRM); yitowilson@gmail.com (CAMW); pablo.conejeros@uv.cl (PC)

  Affiliation Instituto de Física, Pontificia Universidad Católica de Chile, Santiago, Chile

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• Christian A. M. Wilson ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: nbarrera@bio.puc.cl (NPB); jmaze@fis.puc.cl (JRM); yitowilson@gmail.com (CAMW); pablo.conejeros@uv.cl (PC)

  Affiliation Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile

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• Pablo Conejeros

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: nbarrera@bio.puc.cl (NPB); jmaze@fis.puc.cl (JRM); yitowilson@gmail.com (CAMW); pablo.conejeros@uv.cl (PC)

  Affiliation CIGREN. Instituto de Biología. Facultad de Ciencias. Universidad de Valparaíso, Valparaíso, Chile

  http://orcid.org/0000-0001-5073-7121

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