Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines

• Darcy Welch ,

  Contributed equally to this work with: Darcy Welch, Elliot Kahen

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

  http://orcid.org/0000-0003-2753-6684

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• Elliot Kahen ,

  Contributed equally to this work with: Darcy Welch, Elliot Kahen

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliations Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Brooke Fridley ,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Biostatistics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Andrew S. Brohl ,

  Roles Conceptualization, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliations Sarcoma Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Christopher L. Cubitt ,

  Roles Conceptualization, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Translational Research Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Damon R. Reed

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: damon.reed@moffitt.org

  Affiliations Sunshine Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Sarcoma Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Chemical Biology and Molecular Medicine Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Adolescent and Young Adult Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

  http://orcid.org/0000-0002-8238-2465

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