Genome-wide analysis of DNA methylation profile identifies differentially methylated loci associated with human intervertebral disc degeneration

• Akihiro Ikuno ,

  Contributed equally to this work with: Akihiro Ikuno, Koji Akeda

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Laboratory of Molecular & Cellular Biology, Graduate School of Bioresources, Mie University, Tsu, Japan

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• Koji Akeda ,

  Contributed equally to this work with: Akihiro Ikuno, Koji Akeda

  Roles Conceptualization, Investigation, Project administration, Resources, Writing – original draft, Writing – review & editing

  * E-mail: k_akeda@clin.medic.mie-u.ac.jp (KA); katsu@bio.mie-u.ac.jp (KO)

  Affiliation Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan

  http://orcid.org/0000-0001-9468-9387

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• Shin-ichiro Takebayashi,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliation Laboratory of Molecular & Cellular Biology, Graduate School of Bioresources, Mie University, Tsu, Japan

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• Motomu Shimaoka,

  Roles Conceptualization, Funding acquisition, Supervision, Validation, Writing – review & editing

  Affiliation Department of Molecular Pathobiology3, Mie University Graduate School of Medicine, Tsu, Japan

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• Katsuzumi Okumura ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: k_akeda@clin.medic.mie-u.ac.jp (KA); katsu@bio.mie-u.ac.jp (KO)

  Affiliation Laboratory of Molecular & Cellular Biology, Graduate School of Bioresources, Mie University, Tsu, Japan

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• Akihiro Sudo

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan

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