Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity

Sang Woo Kim; Jung-Won Choi; Jong Won Yun; In-Sung Chung; Ho Chan Cho; Seung-Eun Song; Seung-Soon Im; Dae-Kyu Song

doi:10.1371/journal.pone.0222032

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Open Access

Peer-reviewed

Research Article

Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity

Sang Woo Kim,

Roles Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft

Affiliations Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, South Korea, Catholic Kwandong University, International St. Mary’s Hospital, Incheon Metropolitan City, South Korea
⨯
Jung-Won Choi,

Roles Investigation, Methodology, Software, Validation

Affiliations Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, South Korea, Catholic Kwandong University, International St. Mary’s Hospital, Incheon Metropolitan City, South Korea
⨯
Jong Won Yun,

Roles Conceptualization, Data curation, Resources

Affiliation Department of Biotechnology, Daegu University, Kyungsan, Kyungbuk, South Korea
⨯
In-Sung Chung,

Roles Formal analysis, Investigation, Methodology

Affiliation Division of Occupational and Environmental Medicine and Department of Preventive Medicine, Keimyung, University School of Medicine, Daegu, South Korea
⨯
Ho Chan Cho,

Roles Data curation, Validation, Writing – original draft

Affiliation Department of Internal Medicine, Keimyung, University School of Medicine, Daegu, South Korea
⨯
Seung-Eun Song,

Roles Software, Visualization, Writing – review & editing

Affiliation Department of Physiology and Obesity-mediated Disease Research Center, Keimyung, University School of Medicine, Daegu, South Korea
⨯
Seung-Soon Im ,

Roles Conceptualization, Data curation, Validation, Writing – review & editing

* E-mail: ssim@dsmc.or.kr (SSI); dksong@kmu.ac.kr (DKS)

Affiliation Department of Physiology and Obesity-mediated Disease Research Center, Keimyung, University School of Medicine, Daegu, South Korea

http://orcid.org/0000-0002-2743-2108

⨯
Dae-Kyu Song

Roles Conceptualization, Data curation, Validation, Writing – review & editing

* E-mail: ssim@dsmc.or.kr (SSI); dksong@kmu.ac.kr (DKS)

Affiliation Department of Physiology and Obesity-mediated Disease Research Center, Keimyung, University School of Medicine, Daegu, South Korea
⨯

Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity

Sang Woo Kim,
Jung-Won Choi,
Jong Won Yun,
In-Sung Chung,
Ho Chan Cho,
Seung-Eun Song,
Seung-Soon Im,
Dae-Kyu Song

Published: September 10, 2019
https://doi.org/10.1371/journal.pone.0222032

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Obesity
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Diabetes mellitus
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Serum proteins
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Type 2 diabetes
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Biomarkers
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Inflammation
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Protein expression
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HbA1c
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