First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

Gregory Brubaker; Shuhui W. Lorkowski; Kailash Gulshan; Stanley L. Hazen; Valentin Gogonea; Jonathan D. Smith

doi:10.1371/journal.pone.0221915

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Peer-reviewed

Research Article

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

Gregory Brubaker,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Shuhui W. Lorkowski,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Kailash Gulshan,

Roles Investigation, Writing – review & editing

Affiliation Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Stanley L. Hazen,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliations Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Valentin Gogonea,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing

Affiliations Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Chemistry, Cleveland State University, Cleveland, Ohio, United States of America
⨯
Jonathan D. Smith

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: smithj4@ccf.org

Affiliations Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States of America

http://orcid.org/0000-0002-0415-386X

⨯

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

Gregory Brubaker,
Shuhui W. Lorkowski,
Kailash Gulshan,
Stanley L. Hazen,
Valentin Gogonea,
Jonathan D. Smith

Published: January 16, 2020
https://doi.org/10.1371/journal.pone.0221915
See the preprint

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