A conditional inducible JAK2^V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression

• Emilie A. Chapeau ,

  Roles Data curation, Formal analysis, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: emilie.chapeau@novartis.com

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  http://orcid.org/0000-0002-5563-3951

  ⨯
• Emeline Mandon ,

  Roles Formal analysis, Investigation, Methodology, Resources, Validation

  ¶‡ These authors also contributed equally to this work.

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Jason Gill ,

  Roles Methodology, Validation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

  http://orcid.org/0000-0003-0955-6470

  ⨯
• Vincent Romanet ,

  Roles Methodology, Validation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Nicolas Ebel ,

  Roles Methodology, Validation

  ¶‡ These authors also contributed equally to this work.

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Violetta Powajbo,

  Roles Methodology

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Rita Andraos-Rey,

  Roles Methodology

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Zhiyan Qian,

  Roles Methodology, Validation

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Miltos Kininis,

  Roles Investigation

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Sabine Zumstein-Mecker,

  Roles Methodology

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Moriko Ito,

  Roles Supervision

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Nancy E. Hynes,

  Roles Supervision, Writing – review & editing

  Affiliation Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

  ⨯
• Ralph Tiedt,

  Roles Formal analysis, Writing – review & editing

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Francesco Hofmann,

  Roles Conceptualization, Supervision

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Leonid Eshkind,

  Roles Resources

  Affiliation Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany

  ⨯
• Ernesto Bockamp,

  Roles Conceptualization, Resources

  Affiliation Institute for Translational Immunology and Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany

  ⨯
• Bernd Kinzel,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Matthias Mueller,

  Roles Methodology, Supervision

  Affiliation Chemical Biology and Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Masato Murakami ,

  Contributed equally to this work with: Masato Murakami, Fabienne Baffert, Thomas Radimerski

  Roles Conceptualization, Supervision

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
• Fabienne Baffert ,

  Contributed equally to this work with: Masato Murakami, Fabienne Baffert, Thomas Radimerski

  Roles Conceptualization, Investigation, Supervision

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

  ⨯
•  [ ... ],
• Thomas Radimerski

  Contributed equally to this work with: Masato Murakami, Fabienne Baffert, Thomas Radimerski

  Roles Conceptualization, Investigation, Project administration, Writing – original draft

  Affiliation Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland

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