Islets from human donors with higher but not lower hemoglobin A1c levels respond to gastrin treatment in vitro

Ayelet Lenz; Gal Lenz; Hsun Teresa Ku; Kevin Ferreri; Fouad Kandeel

doi:10.1371/journal.pone.0221456

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Open Access

Peer-reviewed

Research Article

Islets from human donors with higher but not lower hemoglobin A1c levels respond to gastrin treatment in vitro

Ayelet Lenz ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ayelet.lenz@gmail.com

Affiliation Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States of America

http://orcid.org/0000-0001-7204-7201

⨯
Gal Lenz,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States of America
⨯
Hsun Teresa Ku,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States of America
⨯
Kevin Ferreri,

Roles Conceptualization, Supervision, Validation, Writing – review & editing

Affiliation Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States of America
⨯
Fouad Kandeel

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Department of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, California, United States of America
⨯

Islets from human donors with higher but not lower hemoglobin A1c levels respond to gastrin treatment in vitro

Ayelet Lenz,
Gal Lenz,
Hsun Teresa Ku,
Kevin Ferreri,
Fouad Kandeel

Published: August 20, 2019
https://doi.org/10.1371/journal.pone.0221456

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Gastrin
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HbA1c
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Somatostatin
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Insulin
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Adults
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Type 2 diabetes
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Diabetes mellitus
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