Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target

Jagbir Singh; Sonam Vijay; Rani Mansuri; Ritu Rawal; Kavita Kadian; Ganesh Chandra Sahoo; Mahesh Kumar; Arun Sharma

doi:10.1371/journal.pone.0221032

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Open Access

Peer-reviewed

Research Article

Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target

Jagbir Singh,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliations Protein Biochemistry and Structural Biology, ICMR-National Institute of Malaria Research, New Delhi, India, Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, India
⨯
Sonam Vijay,

Roles Formal analysis, Methodology, Validation, Writing – original draft

Affiliation Protein Biochemistry and Structural Biology, ICMR-National Institute of Malaria Research, New Delhi, India
⨯
Rani Mansuri,

Roles Data curation, Formal analysis, Methodology, Software, Validation, Writing – original draft

Affiliation School of Pharmaceutical Sciences, ApeejayStya University, Gurugram, India
⨯
Ritu Rawal,

Roles Formal analysis, Investigation, Software, Validation

Affiliation Protein Biochemistry and Structural Biology, ICMR-National Institute of Malaria Research, New Delhi, India
⨯
Kavita Kadian,

Roles Data curation, Formal analysis, Methodology, Validation

Affiliation Protein Biochemistry and Structural Biology, ICMR-National Institute of Malaria Research, New Delhi, India
⨯
Ganesh Chandra Sahoo,

Roles Data curation, Formal analysis, Methodology, Software, Validation

Affiliation Department of Biomedical Sciences, Rajendra Memorial Research Institute, Patna, India
⨯
Mahesh Kumar,

Roles Conceptualization, Formal analysis, Methodology, Software, Validation

Affiliation Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, India
⨯
Arun Sharma

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: arushar@gmail.com

Affiliation Protein Biochemistry and Structural Biology, ICMR-National Institute of Malaria Research, New Delhi, India

http://orcid.org/0000-0002-0928-9926

⨯

Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target

Jagbir Singh,
Sonam Vijay,
Rani Mansuri,
Ritu Rawal,
Kavita Kadian,
Ganesh Chandra Sahoo,
Mahesh Kumar,
Arun Sharma

Published: August 22, 2019
https://doi.org/10.1371/journal.pone.0221032

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