Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration

Hiroyuki Yoshida; Tokiyoshi Matsushita; Erika Kimura; Yukie Fujita; Robert Keany; Toshihiro Ikeda; Masanao Toshimori; Takahiro Imanaka; Masatsugu Nakamura

doi:10.1371/journal.pone.0220887

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Open Access

Peer-reviewed

Research Article

Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration

Hiroyuki Yoshida ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft

* E-mail: hiroyuki.yoshida@santen.com

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan

http://orcid.org/0000-0002-2578-0782

⨯
Tokiyoshi Matsushita,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Erika Kimura,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Yukie Fujita,

Roles Data curation, Formal analysis, Investigation

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Robert Keany,

Roles Data curation, Investigation

Affiliation Research and Development Division, Santen Inc., Emeryville, CA, United States of America
⨯
Toshihiro Ikeda,

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Masanao Toshimori,

Roles Conceptualization, Methodology, Resources, Writing – review & editing

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan
⨯
Takahiro Imanaka,

Roles Conceptualization, Methodology, Resources, Writing – review & editing

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan

http://orcid.org/0000-0002-5780-7564

⨯
Masatsugu Nakamura

Roles Conceptualization, Resources, Supervision, Writing – review & editing

Affiliation Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan
⨯

Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration

Hiroyuki Yoshida,
Tokiyoshi Matsushita,
Erika Kimura,
Yukie Fujita,
Robert Keany,
Toshihiro Ikeda,
Masanao Toshimori,
Takahiro Imanaka,
Masatsugu Nakamura

Published: August 19, 2019
https://doi.org/10.1371/journal.pone.0220887

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Alu elements
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Macular degeneration
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Eyes
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Single nucleotide polymorphisms
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RNA analysis
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Medical risk factors
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Biomarkers
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Genotyping
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