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Open Access
Peer-reviewed
Research Article
Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants
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Jihua Sun,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Biology Department, University of Copenhagen, Copenhagen, Denmark, BGI-Europe, Copenhagen, Denmark
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Christian Theil Have,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing
Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Mette Hollensted,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Niels Grarup,
Roles Conceptualization, Funding acquisition, Methodology, Resources, Writing – review & editing
Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Allan Linneberg,
Roles Investigation, Resources, Writing – review & editing
Affiliations Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Oluf Pedersen,
Roles Conceptualization, Funding acquisition, Methodology, Resources, Writing – review & editing
Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Jens Steen Nielsen,
Roles Investigation, Resources, Writing – review & editing
Affiliation DD2, Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark
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Jørgen Rungby,
Roles Investigation, Resources, Writing – review & editing
Affiliation Bispebjerg Hospital, University of Copenhagen, Denmark Laboratory of Genomics and
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Cramer Christensen,
Roles Investigation, Resources, Writing – review & editing
Affiliation Department of Internal Medicine and Endocrinology, SLB, Hospital Lillebaelt, Vejle, Denmark
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Ivan Brandslund,
Roles Investigation, Resources, Writing – review & editing
Affiliations Department of Clinical Biochemistry, Hospital Lillebaelt, Vejle, Denmark, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark
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Karsten Kristiansen,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliations Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen, Copenhagen, Denmark, BGI-Research, Shenzhen, China
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Wang Jun,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliation iCarbonX, Shenzhen, China
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Torben Hansen,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Anette P. Gjesing
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing
* E-mail: anette.gjesing@sund.ku.dk
Affiliation Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants
- Jihua Sun,
- Christian Theil Have,
- Mette Hollensted,
- Niels Grarup,
- Allan Linneberg,
- Oluf Pedersen,
- Jens Steen Nielsen,
- Jørgen Rungby,
- Cramer Christensen,
- Ivan Brandslund
- Published: August 15, 2019
- https://doi.org/10.1371/journal.pone.0220805