Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension

Mitsuru Seki; Nozomi Furukawa; Norimichi Koitabashi; Masaru Obokata; Simon J. Conway; Hirokazu Arakawa; Masahiko Kurabayashi

doi:10.1371/journal.pone.0220795

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Open Access

Peer-reviewed

Research Article

Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension

Mitsuru Seki ,

Contributed equally to this work with: Mitsuru Seki, Nozomi Furukawa

Roles Data curation, Investigation, Writing – original draft

Affiliations Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan, Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan, Department of Pediatrics, Jichi Medical University, Shimotsuke, Tochigi, Japan
⨯
Nozomi Furukawa ,

Contributed equally to this work with: Mitsuru Seki, Nozomi Furukawa

Roles Investigation

Affiliation Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
⨯
Norimichi Koitabashi ,

Roles Conceptualization, Formal analysis, Investigation, Project administration, Resources, Writing – review & editing

* E-mail: norikoitabashi@gmail.com

Affiliation Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan

http://orcid.org/0000-0002-2113-3422

⨯
Masaru Obokata,

Roles Investigation

Affiliation Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
⨯
Simon J. Conway,

Roles Data curation, Resources

Affiliation Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Hirokazu Arakawa,

Roles Supervision

Affiliation Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
⨯
Masahiko Kurabayashi

Roles Supervision, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
⨯

Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension

Mitsuru Seki,
Nozomi Furukawa,
Norimichi Koitabashi,
Masaru Obokata,
Simon J. Conway,
Hirokazu Arakawa,
Masahiko Kurabayashi

Published: August 22, 2019
https://doi.org/10.1371/journal.pone.0220795

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