The effect of Helicobacter pylori infection and different H. pylori components on the proliferation and apoptosis of gastric epithelial cells and fibroblasts

Weronika Gonciarz; Agnieszka Krupa; Krzysztof Hinc; Michał Obuchowski; Anthony P Moran; Adrian Gajewski; Magdalena Chmiela

doi:10.1371/journal.pone.0220636

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Open Access

Peer-reviewed

Research Article

The effect of Helicobacter pylori infection and different H. pylori components on the proliferation and apoptosis of gastric epithelial cells and fibroblasts

Weronika Gonciarz,

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Łodz, Poland

http://orcid.org/0000-0002-5231-5341

⨯
Agnieszka Krupa,

Roles Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Łodz, Poland
⨯
Krzysztof Hinc,

Roles Methodology

Affiliation Laboratory of Molecular Bacteriology, Intercollegiate Faculty of Biotechnology UG-MUG, Medical University of Gdańsk, Gdansk, Poland
⨯
Michał Obuchowski,

Roles Methodology

Affiliation Laboratory of Molecular Bacteriology, Intercollegiate Faculty of Biotechnology UG-MUG, Medical University of Gdańsk, Gdansk, Poland
⨯
Anthony P Moran †,

† Deceased.

Roles Methodology

Affiliation Department of Microbiology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland
⨯
Adrian Gajewski,

Roles Methodology

Affiliation Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Łodz, Poland
⨯
Magdalena Chmiela

Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

* E-mail: magdalena.chmiela@biol.uni.lodz.pl

Affiliation Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Lodz, Łodz, Poland
⨯

The effect of Helicobacter pylori infection and different H. pylori components on the proliferation and apoptosis of gastric epithelial cells and fibroblasts

Weronika Gonciarz,
Agnieszka Krupa,
Krzysztof Hinc,
Michał Obuchowski,
Anthony P Moran,
Adrian Gajewski,
Magdalena Chmiela

Published: August 7, 2019
https://doi.org/10.1371/journal.pone.0220636

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Helicobacter pylori
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Epithelial cells
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Gastrointestinal infections
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Fibroblasts
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Guinea pigs
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Apoptosis
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Inflammation
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Cell staining
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