Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium

• Yee-Ling Wong ,

  Contributed equally to this work with: Yee-Ling Wong, Pirro Hysi, Gemmy Cheung

  Roles Project administration, Writing – original draft, Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, R&D Vision Sciences AMERA, Essilor International, Singapore, Singapore

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• Pirro Hysi ,

  Contributed equally to this work with: Yee-Ling Wong, Pirro Hysi, Gemmy Cheung

  Roles Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Section of Academic Ophthalmology, School of Life Course Sciences, King’s College London, London, United Kingdom

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• Gemmy Cheung ,

  Contributed equally to this work with: Yee-Ling Wong, Pirro Hysi, Gemmy Cheung

  Roles Methodology, Writing – original draft, Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

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• Milly Tedja,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

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• Quan V. Hoang,

  Roles Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore, Department of Ophthalmology, Columbia University Medical Center, New York, NY, United States of America

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• Stuart W. J. Tompson,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison WI, United States of America

  http://orcid.org/0000-0001-9788-6730

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• Kristina N. Whisenhunt,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison WI, United States of America

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• Virginie Verhoeven,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands

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• Wanting Zhao,

  Roles Formal analysis, Project administration, Writing – review & editing

  Affiliation Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore

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• Moritz Hess,

  Roles Methodology, Writing – review & editing

  Affiliations Institute for Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg—University Mainz, Mainz, Germany, Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center—University of Freiburg, Freiburg, Germany

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• Chee-Wai Wong,

  Roles Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore

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• Annette Kifley,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology, Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia

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• Yoshikatsu Hosoda,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology and Visual Sciences, University Graduate School of Medicine, Kyoto, Japan

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• Annechien E. G. Haarman,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

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• Susanne Hopf,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology, University Medical Center of the Johannes Gutenberg—University Mainz, Mainz, Germany

  http://orcid.org/0000-0002-7989-9420

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• Panagiotis Laspas,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology, University Medical Center of the Johannes Gutenberg—University Mainz, Mainz, Germany

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• Sonoko Sensaki,

  Roles Project administration, Writing – review & editing

  Affiliation Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore

  ⨯
• Xueling Sim,

  Roles Methodology, Project administration, Writing – review & editing

  Affiliation Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore

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• Masahiro Miyake,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology and Visual Sciences, University Graduate School of Medicine, Kyoto, Japan

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• Akitaka Tsujikawa,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology and Visual Sciences, University Graduate School of Medicine, Kyoto, Japan

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• Ecosse Lamoureux,

  Roles Methodology, Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore

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• Kyoko Ohno-Matsui,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan

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• Stefan Nickels,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology, University Medical Center of the Johannes Gutenberg—University Mainz, Mainz, Germany

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• Paul Mitchell,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Ophthalmology, Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia

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• Tien-Yin Wong,

  Roles Methodology, Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

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• Jie Jin Wang,

  Roles Methodology, Writing – review & editing

  Affiliation Duke-NUS Medical School, Singapore, Singapore

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• Christopher J. Hammond,

  Roles Methodology, Writing – review & editing

  Affiliation Section of Academic Ophthalmology, School of Life Course Sciences, King’s College London, London, United Kingdom

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• Veluchamy A. Barathi,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

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• Ching-Yu Cheng,

  Roles Methodology, Writing – review & editing

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

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• Kenji Yamashiro,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Ophthalmology and Visual Sciences, University Graduate School of Medicine, Kyoto, Japan, Department of Ophthalmology, Otsu Red-Cross Hospital, Otsu, Japan

  http://orcid.org/0000-0001-9354-8558

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• Terri L. Young ,

  Roles Methodology, Supervision, Writing – review & editing

  ¶‡ These authors jointly supervised this work.

  Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison WI, United States of America

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• Caroline C. W. Klaver ,

  Roles Formal analysis, Supervision, Writing – review & editing

  ¶‡ These authors jointly supervised this work.

  Affiliations Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands

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• Seang-Mei Saw ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ephssm@nus.edu.sg

  ¶‡ These authors jointly supervised this work.

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore, Duke-NUS Medical School, Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore

  http://orcid.org/0000-0001-7166-796X

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•  [ ... ],
• The Consortium of Refractive Error, Myopia (CREAM)

  ¶Complete membership of the CREAM Consortium is provided in the Supporting Information (S1 Text).

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