Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census

• Sony Malhotra ,

  Contributed equally to this work with: Sony Malhotra, Ali F. Alsulami

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: s.malhotra@mail.cryst.bbk.ac.uk (SM); tlb20@cam.ac.uk (TLB)

  Current address: Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck College, University of London, London, United Kingdom.

  Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

  http://orcid.org/0000-0002-3165-9081

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• Ali F. Alsulami ,

  Contributed equally to this work with: Sony Malhotra, Ali F. Alsulami

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

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• Yang Heiyun,

  Roles Formal analysis

  Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

  http://orcid.org/0000-0002-7670-1626

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• Bernardo Montano Ochoa,

  Roles Software

  Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

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• Harry Jubb,

  Roles Writing – review & editing

  Affiliation Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom

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• Simon Forbes,

  Roles Writing – review & editing

  Affiliation Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom

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• Tom L. Blundell

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: s.malhotra@mail.cryst.bbk.ac.uk (SM); tlb20@cam.ac.uk (TLB)

  Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

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