Empowering therapeutic antibodies with IFN-α for cancer immunotherapy

Jun Guo; Yu Xiao; Ramesh Iyer; Xin Lu; Marc Lake; Uri Ladror; John Harlan; Tanushree Samanta; Medha Tomlinson; Gail Bukofzer; Cherrie Donawho; Alex Shoemaker; Tzu-Hsuan Huang

doi:10.1371/journal.pone.0219829

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Open Access

Peer-reviewed

Research Article

Empowering therapeutic antibodies with IFN-α for cancer immunotherapy

Jun Guo,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America
⨯
Yu Xiao,

Roles Data curation, Investigation

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America
⨯
Ramesh Iyer,

Roles Investigation, Methodology, Resources

Affiliation Global Protein Sciences, AbbVie Inc., North Chicago, United States of America
⨯
Xin Lu,

Roles Data curation, Investigation, Methodology

Affiliation Genomics Research Center, AbbVie Inc., North Chicago, United States of America
⨯
Marc Lake,

Roles Data curation, Methodology

Affiliation Global Protein Sciences, AbbVie Inc., North Chicago, United States of America
⨯
Uri Ladror,

Roles Data curation, Investigation, Methodology

Affiliation Global Protein Sciences, AbbVie Inc., North Chicago, United States of America
⨯
John Harlan,

Roles Data curation, Investigation, Methodology

Affiliation Global Protein Sciences, AbbVie Inc., North Chicago, United States of America

http://orcid.org/0000-0003-0948-7823

⨯
Tanushree Samanta,

Roles Data curation, Investigation

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America
⨯
Medha Tomlinson,

Roles Data curation, Investigation, Methodology

Affiliation Global Biologics, AbbVie Bioresearch Center, Worcester, United States of America
⨯
Gail Bukofzer,

Roles Data curation, Investigation, Methodology

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America
⨯
Cherrie Donawho,

Roles Data curation, Investigation, Methodology

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America
⨯
Alex Shoemaker,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America
⨯
Tzu-Hsuan Huang

Roles Conceptualization, Investigation, Supervision, Writing – review & editing

* E-mail: leon.huang@abbvie.com, tzu-hsuan@pfizer.com

Affiliation Oncology Discovery, AbbVie Inc., North Chicago, United States of America

http://orcid.org/0000-0003-0650-582X

⨯

Empowering therapeutic antibodies with IFN-α for cancer immunotherapy

Jun Guo,
Yu Xiao,
Ramesh Iyer,
Xin Lu,
Marc Lake,
Uri Ladror,
John Harlan,
Tanushree Samanta,
Medha Tomlinson,
Gail Bukofzer

Published: August 8, 2019
https://doi.org/10.1371/journal.pone.0219829

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