Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway

• Anusi Sarkar,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada, Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada

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• Ayan Chanda,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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• Suresh C. Regmi,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada

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• Kunal Karve,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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• Lili Deng,

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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• Gregory D. Jay,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  Affiliation Department of Emergency Medicine—Alpert Medical School & School of Engineering, Brown University, Providence, Rhode Island, United States of America

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• Frank R. Jirik,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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• Tannin A. Schmidt ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: sbonni@ucalgary.ca (SB); tschmidt@uchc.edu (TS)

  Affiliations Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada, Biomedical Engineering Department, University of Connecticut Health Center, Farmington, Connecticut, United States of America

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• Shirin Bonni

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: sbonni@ucalgary.ca (SB); tschmidt@uchc.edu (TS)

  Affiliation The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

  http://orcid.org/0000-0002-2649-8738

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