A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

Dongyun Lin; Zhiping Lin; Jiuwen Cao; Ramraj Velmurugan; E. Sally Ward; Raimund J. Ober

doi:10.1371/journal.pone.0218931

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Open Access

Peer-reviewed

Research Article

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

Dongyun Lin,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore
⨯
Zhiping Lin ,

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

* E-mail: EZPLIN@ntu.edu.sg

Affiliation School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore

http://orcid.org/0000-0002-1587-1226

⨯
Jiuwen Cao,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Key Lab for IOT and Information Fusion Technology of Zhejiang, Hangzhou Dianzi University, Hangzhou, China
⨯
Ramraj Velmurugan,

Roles Resources, Validation

Affiliation Department of Biomedical Engineering, Texas A&M University, College Station, TX, United States of America
⨯
E. Sally Ward,

Roles Project administration, Supervision

Affiliations Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center, College Station, TX, United States of America, Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX, United States of America, Cancer Sciences Unit, Centre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
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Raimund J. Ober

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliations Department of Biomedical Engineering, Texas A&M University, College Station, TX, United States of America, Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center, College Station, TX, United States of America, Cancer Sciences Unit, Centre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

Dongyun Lin,
Zhiping Lin,
Jiuwen Cao,
Ramraj Velmurugan,
E. Sally Ward,
Raimund J. Ober

Published: June 27, 2019
https://doi.org/10.1371/journal.pone.0218931

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Fluorescence imaging
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