Dexmedetomidine-induced cardioprotection is mediated by inhibition of high mobility group box-1 and the cholinergic anti-inflammatory pathway in myocardial ischemia-reperfusion injury

• Juan Zhang ,

  Contributed equally to this work with: Juan Zhang, Fan Xia

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

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• Fan Xia ,

  Contributed equally to this work with: Juan Zhang, Fan Xia

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

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• Haifeng Zhao,

  Roles Methodology

  Affiliation Department of Pathology, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou Science and Technology Town Hospital, Suzhou, China

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• Ke Peng,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

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• Huayue Liu,

  Roles Investigation

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

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• Xiaowen Meng,

  Roles Writing – review & editing

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

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• Chen Chen,

  Roles Investigation

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

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• Fuhai Ji

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: jifuhaisuda@163.com

  Affiliation Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, China

  http://orcid.org/0000-0001-6649-665X

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