Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice

• Florence Njau ,

  Contributed equally to this work with: Florence Njau, Nelli Shushakova

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Njau.Florence@mh-hannover.de

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  http://orcid.org/0000-0002-6397-991X

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• Nelli Shushakova ,

  Contributed equally to this work with: Florence Njau, Nelli Shushakova

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  ⨯
• Heiko Schenk,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  ⨯
• Vera Christine Wulfmeyer,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  ⨯
• Robin Bollin,

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  ⨯
• Jan Menne,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  ⨯
• Hermann Haller

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Division of Nephrology, Hannover Medical School, Hannover, Germany

  ⨯