Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway

• Eveline Kersten ,

  Contributed equally to this work with: Eveline Kersten, Sascha Dammeier

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands

  http://orcid.org/0000-0003-3556-9718

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• Sascha Dammeier ,

  Contributed equally to this work with: Eveline Kersten, Sascha Dammeier

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Institute for Ophthalmic Research, Core Facility for Medical Bioanalytics, University of Tübingen, Tübingen, Germany

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• Soufiane Ajana,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation University of Bordeaux, Inserm, Bordeaux Population Health Research Center, LEHA team, UMR 1219, Bordeaux, France

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• Joannes M. M. Groenewoud,

  Roles Formal analysis, Methodology

  Affiliation Department of Epidemiology, Biostatistics, and Health Technology Assessment, Radboud university medical center, Nijmegen, the Netherlands

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• Marius Codrea,

  Roles Formal analysis, Methodology

  Affiliation Quantitative Biology Center, University of Tübingen, Tübingen, Germany

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• Franziska Klose,

  Roles Formal analysis

  Affiliation Institute for Ophthalmic Research, Core Facility for Medical Bioanalytics, University of Tübingen, Tübingen, Germany

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• Yara T. Lechanteur,

  Roles Conceptualization, Data curation, Methodology

  Affiliation Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands

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• Sascha Fauser,

  Roles Supervision, Writing – review & editing

  Affiliations F. Hoffmann - La Roche AG, Basel, Switzerland, Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany

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• Marius Ueffing,

  Roles Supervision, Writing – review & editing

  Affiliation Institute for Ophthalmic Research, Core Facility for Medical Bioanalytics, University of Tübingen, Tübingen, Germany

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• Cécile Delcourt,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation University of Bordeaux, Inserm, Bordeaux Population Health Research Center, LEHA team, UMR 1219, Bordeaux, France

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• Carel B. Hoyng,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands

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• Eiko K. de Jong,

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands

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• Anneke I. den Hollander ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: Anneke.denhollander@radboudumc.nl

  Affiliations Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands, Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands

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• EYE-RISK Consortium

  ¶Membership of the EYE-RISK Consortium is provided in the Acknowledgments.

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