A design of experiments approach for the rapid formulation of a chemically defined medium for metabolic profiling of industrially important microbes

Chloe Singleton; James Gilman; Jessica Rollit; Kun Zhang; David A. Parker; John Love

doi:10.1371/journal.pone.0218208

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Open Access

Peer-reviewed

Research Article

A design of experiments approach for the rapid formulation of a chemically defined medium for metabolic profiling of industrially important microbes

Chloe Singleton ,

Contributed equally to this work with: Chloe Singleton, James Gilman

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation The Exeter Microbial Biofuels Group, College of Life and Environmental Sciences, The University of Exeter, Exeter, Devon, United Kingdom

http://orcid.org/0000-0001-7862-4321

⨯
James Gilman ,

Contributed equally to this work with: Chloe Singleton, James Gilman

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation The Exeter Microbial Biofuels Group, College of Life and Environmental Sciences, The University of Exeter, Exeter, Devon, United Kingdom
⨯
Jessica Rollit,

Roles Formal analysis, Investigation, Methodology, Validation

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
⨯
Kun Zhang,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Shell Technology Centre, Houston, Texas, United States of America
⨯
David A. Parker,

Roles Conceptualization, Project administration, Writing – review & editing

Affiliations The Exeter Microbial Biofuels Group, College of Life and Environmental Sciences, The University of Exeter, Exeter, Devon, United Kingdom, Shell Technology Centre, Houston, Texas, United States of America
⨯
John Love

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: J.Love@exeter.ac.uk

Affiliation The Exeter Microbial Biofuels Group, College of Life and Environmental Sciences, The University of Exeter, Exeter, Devon, United Kingdom
⨯

A design of experiments approach for the rapid formulation of a chemically defined medium for metabolic profiling of industrially important microbes

Chloe Singleton,
James Gilman,
Jessica Rollit,
Kun Zhang,
David A. Parker,
John Love

Published: June 12, 2019
https://doi.org/10.1371/journal.pone.0218208

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