PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses

• Marta Bueno,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Aging Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0001-7140-9899

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• Daniel Zank,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Ivette Buendia-Roldán,

  Roles Data curation, Writing – review & editing

  Affiliation Instituto Nacional de Enfermedades Respiratorias “Ismael Cosio Villegas”, Mexico City, Distrito Federal, México

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• Kaitlin Fiedler,

  Roles Data curation, Writing – review & editing

  Affiliation Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Brenton G. Mays,

  Roles Data curation, Writing – review & editing

  Affiliation Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Diana Alvarez,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Aging Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• John Sembrat,

  Roles Data curation, Resources, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, The Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Brian Kimball,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, The Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Jordan K. Bullock,

  Roles Data curation, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, The Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• James L. Martin,

  Roles Data curation, Writing – review & editing

  Affiliations Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Metabolism and Mitochondrial Medicine, Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Mehdi Nouraie,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, The Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Brett A. Kaufman,

  Roles Formal analysis, Methodology, Resources, Writing – review & editing

  Affiliations Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Metabolism and Mitochondrial Medicine, Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Mauricio Rojas,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosio Villegas”, Mexico City, Distrito Federal, México, McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Annie Pardo,

  Roles Conceptualization, Writing – review & editing

  Affiliation Facultad de Ciencias, Universidad Nacional Autónoma de México, Mexico City, Distrito Federal, México

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• Moisés Selman,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Instituto Nacional de Enfermedades Respiratorias “Ismael Cosio Villegas”, Mexico City, Distrito Federal, México

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•  [ ... ],
• Ana L. Mora

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  * E-mail: anamora@pitt.edu

  Affiliations Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Aging Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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