Impact of early adverse life events and sex on functional brain networks in patients with urological chronic pelvic pain syndrome (UCPPS): A MAPP Research Network study

• Arpana Gupta ,

  Contributed equally to this work with: Arpana Gupta, Ravi R. Bhatt

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States of America, Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA, United States of America

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• Ravi R. Bhatt ,

  Contributed equally to this work with: Arpana Gupta, Ravi R. Bhatt

  Roles Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States of America

  http://orcid.org/0000-0003-2498-8888

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• Bruce D. Naliboff,

  Roles Conceptualization, Writing – review & editing

  Affiliations G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States of America, Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA, United States of America

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• Jason J. Kutch,

  Roles Conceptualization, Writing – review & editing

  Affiliation USC Division of Biokinesiology and Physical Therapy, Los Angeles, CA, United States of America

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• Jennifer S. Labus,

  Roles Writing – review & editing

  Affiliations G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States of America, Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA, United States of America

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• Priten P. Vora,

  Roles Visualization

  Affiliations G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States of America, Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA, United States of America

  http://orcid.org/0000-0001-8367-5377

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• Mher Alaverdyan,

  Roles Formal analysis

  Affiliation G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America

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• Andrew Schrepf,

  Roles Writing – review & editing

  Affiliations Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, United States of America, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, United States of America

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• Susan Lutgendorf,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, United States of America, Department of Urology, University of Iowa, Iowa City, IA, United States of America, Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, United States of America

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• Emeran A. Mayer ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: emayer@ucla.edu

  Affiliations G. Oppenheimer Center for Neurobiology of Stress and Resilience, UCLA, Los Angeles, CA, United States of America, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States of America, Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA, United States of America, Ahmanson-Lovelace Brain Mapping Center, UCLA, Los Angeles, CA, United States of America

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• MAPP Research Network

  ¶Membership of the MAPP Research Network is provided in S4 Table.

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