An one-pot two-step automated synthesis of [¹⁸F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans

• Ya-Yao Huang ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: careyyh@ntuh.gov.tw (Y-YH); shiue@ntuh.gov.tw (C-YS)

  Affiliation PET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan

  http://orcid.org/0000-0002-3460-7922

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• Ming-Jang Chiu,

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Resources

  Affiliations Molecular Imaging Center, National Taiwan University, Taipei, Taiwan, Departments of Neurology, National Taiwan University Hospital, Taipei, Taiwan, Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Zhongzheng Dist., Taipei, Taiwan, Department of Psychology, National Taiwan University, Taipei, Taiwan, Graduate Institute of Biomedical Engineering and Bio-informatics, National Taiwan University, Taipei, Taiwan

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• Ruoh-Fang Yen,

  Roles Formal analysis, Funding acquisition, Investigation, Resources

  Affiliations PET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan, Molecular Imaging Center, National Taiwan University, Taipei, Taiwan, Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan

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• Chia-Ling Tsai,

  Roles Data curation, Investigation, Methodology, Project administration

  Affiliation PET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan

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• Hao-Yu Hsieh,

  Roles Data curation, Investigation, Methodology

  Affiliation School of Pharmacy, College of Medicine, National Taiwan University, Zhongzheng Dist., Taipei, Taiwan

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• Ching-Hung Chiu,

  Roles Data curation, Investigation, Project administration, Validation

  Affiliation PET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan

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• Chi-Han Wu,

  Roles Formal analysis, Investigation, Project administration

  Affiliation Molecular Imaging Center, National Taiwan University, Taipei, Taiwan

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• Ling-Wei Hsin,

  Roles Data curation, Investigation, Methodology, Project administration, Resources

  Affiliations Molecular Imaging Center, National Taiwan University, Taipei, Taiwan, School of Pharmacy, College of Medicine, National Taiwan University, Zhongzheng Dist., Taipei, Taiwan

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• Kai-Yuan Tzen,

  Roles Funding acquisition, Project administration, Resources, Supervision

  Affiliations PET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan, Molecular Imaging Center, National Taiwan University, Taipei, Taiwan

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• Cheng-Yi Cheng,

  Roles Funding acquisition, Investigation, Resources

  Affiliation PET Center, Department of Nuclear Medicine, Tri-Service General Hospital, Neihu, Taipei, Taiwan

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• Kuo-Hsing Ma,

  Roles Investigation, Methodology, Resources, Supervision

  Affiliation Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan

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• Chyng-Yann Shiue

  Roles Conceptualization, Project administration, Supervision, Visualization, Writing – review & editing

  * E-mail: careyyh@ntuh.gov.tw (Y-YH); shiue@ntuh.gov.tw (C-YS)

  Affiliations PET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan, Molecular Imaging Center, National Taiwan University, Taipei, Taiwan, PET Center, Department of Nuclear Medicine, Tri-Service General Hospital, Neihu, Taipei, Taiwan

  http://orcid.org/0000-0002-8548-8871

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