Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice

• Timothy Affolter,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Global Pathology, Pfizer Drug Safety Research and Development, La Jolla, California, United States of America

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• Heather P. Llewellyn,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Global Pathology, Pfizer Drug Safety Research and Development, La Jolla, California, United States of America

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• Derek W. Bartlett,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliation Medicine Design, Pfizer Worldwide Research and Development, La Jolla, California, United States of America

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• Qing Zong,

  Roles Data curation, Investigation, Methodology

  Affiliation Biomarkers, Pfizer Drug Safety Research and Development, La Jolla, California, United States of America

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• Shuhua Xia,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Investigative Toxicology, Drug Safety Research and Development, Groton, Connecticut, United States of America

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• Vince Torti,

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision

  Affiliation General Toxicology, Drug Safety Research and Development La Jolla, California, United States of America

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• Changhua Ji

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: changhua.ji2@pfizer.com

  Affiliation Global Pathology, Pfizer Drug Safety Research and Development, La Jolla, California, United States of America

  http://orcid.org/0000-0002-3329-6421

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