Kinetic characteristics of propofol-induced inhibition of electron-transfer chain and fatty acid oxidation in human and rodent skeletal and cardiac muscles

Tomáš Urban; Petr Waldauf; Adéla Krajčová; Kateřina Jiroutková; Milada Halačová; Valér Džupa; Libor Janoušek; Eva Pokorná; František Duška

doi:10.1371/journal.pone.0217254

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Open Access

Peer-reviewed

Research Article

Kinetic characteristics of propofol-induced inhibition of electron-transfer chain and fatty acid oxidation in human and rodent skeletal and cardiac muscles

Tomáš Urban,

Roles Formal analysis, Investigation, Writing – original draft

Affiliation OXYLAB – Mitochondrial Physiology Lab: Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic
⨯
Petr Waldauf,

Roles Formal analysis

Affiliation OXYLAB – Mitochondrial Physiology Lab: Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic
⨯
Adéla Krajčová,

Roles Investigation, Writing – original draft

Affiliation OXYLAB – Mitochondrial Physiology Lab: Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic
⨯
Kateřina Jiroutková,

Roles Investigation, Writing – original draft

Affiliation OXYLAB – Mitochondrial Physiology Lab: Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic

http://orcid.org/0000-0003-4102-9769

⨯
Milada Halačová,

Roles Formal analysis

Affiliation OXYLAB – Mitochondrial Physiology Lab: Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic
⨯
Valér Džupa,

Roles Resources

Affiliation Department of Orthopaedics and Traumatology, Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic
⨯
Libor Janoušek,

Roles Resources

Affiliation Transplantation Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
⨯
Eva Pokorná,

Roles Resources

Affiliation Department of Organ Recovery and Transplantation Databases, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
⨯
František Duška

Roles Conceptualization, Investigation, Project administration, Visualization, Writing – original draft

* E-mail: frantisek.duska@lf3.cuni.cz

Affiliation OXYLAB – Mitochondrial Physiology Lab: Charles University, 3rd Faculty of Medicine and FNKV University Hospital, Prague, Czech Republic

http://orcid.org/0000-0003-1559-4078

⨯

Kinetic characteristics of propofol-induced inhibition of electron-transfer chain and fatty acid oxidation in human and rodent skeletal and cardiac muscles

Tomáš Urban,
Petr Waldauf,
Adéla Krajčová,
Kateřina Jiroutková,
Milada Halačová,
Valér Džupa,
Libor Janoušek,
Eva Pokorná,
František Duška

Published: October 4, 2019
https://doi.org/10.1371/journal.pone.0217254

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Skeletal muscles
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Cardiac muscles
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Mitochondria
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Fatty acids
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Rodents
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Oxidation
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