Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancer

• Akiko Suzuki ,

  Contributed equally to this work with: Akiko Suzuki, Sachin Puri

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft

  Affiliation Center for Biologics Evaluation & Research, Food Drug Administration, Bethesda, Maryland, United States of America

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• Sachin Puri ,

  Contributed equally to this work with: Akiko Suzuki, Sachin Puri

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Molecular & Tumor Immunology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, Oregon, United States of America

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• Pamela Leland,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Center for Biologics Evaluation & Research, Food Drug Administration, Bethesda, Maryland, United States of America

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• Ankit Puri,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Center for Biologics Evaluation & Research, Food Drug Administration, Bethesda, Maryland, United States of America

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• Tarsem Moudgil,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Molecular & Tumor Immunology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, Oregon, United States of America

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• Bernard A. Fox,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliations Molecular & Tumor Immunology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center, Portland, Oregon, United States of America, Department of Molecular Microbiology and Immunology, OHSU, Portland, Oregon, United States of America

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• Raj K. Puri,

  Roles Conceptualization, Investigation, Validation, Writing – review & editing

  Affiliation Center for Biologics Evaluation & Research, Food Drug Administration, Bethesda, Maryland, United States of America

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• Bharat H. Joshi

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: bharat.joshi@fda.hhs.gov

  Affiliation Center for Biologics Evaluation & Research, Food Drug Administration, Bethesda, Maryland, United States of America

  http://orcid.org/0000-0001-5246-3881

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