Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis

• Ke Shi,

  Roles Conceptualization, Data curation, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Seunghee Cho,

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliations Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, United States of America

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• Kelly G. Aukema,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliations Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, United States of America

  http://orcid.org/0000-0003-3566-7334

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• Thomas Lee,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, United States of America

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• Asim K. Bera,

  Roles Investigation

  Affiliations Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, United States of America

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• Jennifer L. Seffernick,

  Roles Conceptualization, Writing – original draft

  Affiliations Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, United States of America

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• Lawrence P. Wackett ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: aihar001@umn.edu (HA); wacke003@umn.edu (LPW)

  Affiliations Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, United States of America, Microbial and Plant Genomics Institute, University of Minnesota, St. Paul, Minnesota, United States of America

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• Hideki Aihara

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: aihar001@umn.edu (HA); wacke003@umn.edu (LPW)

  Affiliation Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America

  http://orcid.org/0000-0001-7508-6230

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