Short-term fish oil supplementation applied in presymptomatic stage of Alzheimer's disease enhances microglial/macrophage barrier and prevents neuritic dystrophy in parietal cortex of 5xFAD mouse model

Milena Jović; Nataša Lončarević-Vasiljković; Sanja Ivković; Jelena Dinić; Desanka Milanović; Berislav Zlokovic; Selma Kanazir

doi:10.1371/journal.pone.0216726

Loading metrics

Open Access

Peer-reviewed

Research Article

Short-term fish oil supplementation applied in presymptomatic stage of Alzheimer's disease enhances microglial/macrophage barrier and prevents neuritic dystrophy in parietal cortex of 5xFAD mouse model

Milena Jović ,

Contributed equally to this work with: Milena Jović, Nataša Lončarević-Vasiljković, Sanja Ivković

Roles Conceptualization, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft

Affiliation Department of Neurobiology, Institute for Biological Research ‘Sinisa Stankovic’, University of Belgrade, Belgrade, Serbia
⨯
Nataša Lončarević-Vasiljković ,

Contributed equally to this work with: Milena Jović, Nataša Lončarević-Vasiljković, Sanja Ivković

Roles Conceptualization, Data curation, Investigation, Software, Writing – original draft, Writing – review & editing

* E-mail: natasa.loncarevic@ibiss.bg.ac.rs (NLV); selkan@ibiss.bg.ac.rs (SK)

Affiliation Department of Neurobiology, Institute for Biological Research ‘Sinisa Stankovic’, University of Belgrade, Belgrade, Serbia

http://orcid.org/0000-0002-8350-1390

⨯
Sanja Ivković ,

Contributed equally to this work with: Milena Jović, Nataša Lončarević-Vasiljković, Sanja Ivković

Roles Conceptualization, Writing – review & editing

Affiliation Department of Neurobiology, Institute for Biological Research ‘Sinisa Stankovic’, University of Belgrade, Belgrade, Serbia
⨯
Jelena Dinić,

Roles Formal analysis, Software, Visualization

Affiliation Department of Neurobiology, Institute for Biological Research ‘Sinisa Stankovic’, University of Belgrade, Belgrade, Serbia
⨯
Desanka Milanović,

Roles Formal analysis, Software, Visualization

Affiliation Department of Neurobiology, Institute for Biological Research ‘Sinisa Stankovic’, University of Belgrade, Belgrade, Serbia
⨯
Berislav Zlokovic,

Roles Writing – review & editing

Affiliation Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America
⨯
Selma Kanazir

Roles Conceptualization, Data curation, Supervision, Writing – review & editing

* E-mail: natasa.loncarevic@ibiss.bg.ac.rs (NLV); selkan@ibiss.bg.ac.rs (SK)

Affiliation Department of Neurobiology, Institute for Biological Research ‘Sinisa Stankovic’, University of Belgrade, Belgrade, Serbia
⨯

Short-term fish oil supplementation applied in presymptomatic stage of Alzheimer's disease enhances microglial/macrophage barrier and prevents neuritic dystrophy in parietal cortex of 5xFAD mouse model

Milena Jović,
Nataša Lončarević-Vasiljković,
Sanja Ivković,
Jelena Dinić,
Desanka Milanović,
Berislav Zlokovic,
Selma Kanazir

Published: May 16, 2019
https://doi.org/10.1371/journal.pone.0216726

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Alzheimer's disease
Is the Subject Area "Alzheimer's disease" applicable to this article?

Thanks for your feedback.
Parietal lobe
Is the Subject Area "Parietal lobe" applicable to this article?

Thanks for your feedback.
Oils
Is the Subject Area "Oils" applicable to this article?

Thanks for your feedback.
Neurites
Is the Subject Area "Neurites" applicable to this article?

Thanks for your feedback.
Microglial cells
Is the Subject Area "Microglial cells" applicable to this article?

Thanks for your feedback.
Amyloid plaques
Is the Subject Area "Amyloid plaques" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Phagocytosis
Is the Subject Area "Phagocytosis" applicable to this article?

Thanks for your feedback.