Age at diagnosis, but not HPV type, is strongly associated with clinical course in recurrent respiratory papillomatosis

• Farrel J. Buchinsky ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: fjbuch@gmail.com

  Affiliation Respiratory Papillomatosis Program, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0002-2830-6023

  ⨯
• William L. Valentino,

  Roles Visualization, Writing – original draft, Writing – review & editing

  Affiliation Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

  http://orcid.org/0000-0002-9540-626X

  ⨯
• Nicole Ruszkay,

  Roles Visualization, Writing – original draft, Writing – review & editing

  Affiliation Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

  ⨯
• Evan Powell,

  Roles Data curation, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Pittsburgh Clinical Genomics Laboratory, UPMC Magee—Women’s Hospital, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Craig S. Derkay,

  Roles Conceptualization, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology—Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, Virginia, United States of America

  ⨯
• Riaz Y. Seedat,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otorhinolaryngology, University of the Free State, Bloemfontein, South Africa

  http://orcid.org/0000-0002-9774-334X

  ⨯
• Virgilijus Uloza,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otorhinolaryngology, Lithuanian University of Health Sciences, Kaunas, Lithuania

  ⨯
• Frederik G. Dikkers,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otorhinolaryngology, Amsterdam UMC, Amsterdam, Netherlands

  ⨯
• David E. Tunkel,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

  ⨯
• Sukgi S. Choi,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology and Communication Enhancement, Harvard Medical School—Boston Children's Hospital, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0002-5448-1546

  ⨯
• Anthony J. Mortelliti,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology and Communication Sciences, State University of New York Upstate Medical University, Syracuse, New York, United States of America

  ⨯
• Paolo Campisi,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology—Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Juan C. Ospina,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Unit of Otorhinolaryngology and Maxillofacial Surgery, Pontificia Universidad Javeriana-Hospital San Ignacio, Bogotá, Colombia

  http://orcid.org/0000-0001-7806-5355

  ⨯
• Adam J. Donne,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Paediatric Otolaryngology, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom

  ⨯
• Robert T. Sataloff,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology—Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

  ⨯
• Stephen F. Conley,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

  ⨯
• John E. McClay,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Frisco ENT for Children, Dallas, Texas, United States of America

  ⨯
• Ellen M. Friedman,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Otolaryngology and Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

  ⨯
• Lisa Elden,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department Otolaryngology at Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Dale A. Tylor,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation ENT Associates of Santa Barbara, Santa Barbara, California, United States of America

  ⨯
• Clark A. Rosen,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology, University of California San Francisco, San Francisco, California, United States of America

  http://orcid.org/0000-0003-1571-1086

  ⨯
• Libby J. Smith,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation University of Pittsburgh Voice Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Graeme J. Copley,

  Roles Investigation, Resources

  Affiliation Red Cross War Memorial Children’s Hospital, Cape Town, South Africa

  ⨯
• David E. Karas,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Section of Otolaryngology, Yale University School of Medicine, New Haven, Connecticut, United States of America

  ⨯
• John M. Schweinfurth,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

  http://orcid.org/0000-0001-8713-4017

  ⨯
• Charles M. Myer III,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology–Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

  ⨯
• Brian J. Wiatrak,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Pediatric Otolaryngology, Children's Hospital of Alabama, Birmingham, Alabama, United States of America

  ⨯
• Joseph E. Dohar,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh—UPMC, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Steven E. Sobol,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department Otolaryngology at Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Robert W. Bastian,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Bastian Voice Institute, Downers Grove, Illinois, United States of America

  ⨯
• Richard J. H. Smith,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Pediatric Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America

  ⨯
• Marshall E. Smith,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Division of Otolaryngology—Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

  ⨯
• Abebe M. Wassie,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Otolaryngology—Head and Neck Surgery, Addis Ababa University, Addis Ababa, Ethiopia

  ⨯
• James C. Post,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision

  Affiliation Respiratory Papillomatosis Program, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America

  ⨯
•  [ ... ],
• Garth D. Ehrlich

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Departments of Microbiology and Immunology, and Otolaryngology—Head and Neck Surgery and Center for Genomic Sciences, Institute of Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

  http://orcid.org/0000-0003-0341-8771

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