Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in Kras^G12D mice

• Fang Hao ,

  Contributed equally to this work with: Fang Hao, Qinhong Xu

  Roles Investigation, Methodology

  Affiliations Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Tianjin Medical University, Tianjin, China

  ⨯
• Qinhong Xu ,

  Contributed equally to this work with: Fang Hao, Qinhong Xu

  Roles Investigation

  Affiliations Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Xi’an Jiaotong University, Xi'an, China

  http://orcid.org/0000-0003-0654-5290

  ⨯
• Jing Wang,

  Roles Investigation, Methodology

  Affiliations Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Xi’an Jiaotong University, Xi'an, China

  ⨯
• Shuo Yu,

  Roles Investigation, Methodology

  Affiliations Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Xi’an Jiaotong University, Xi'an, China

  ⨯
• Hui-Hua Chang,

  Roles Investigation

  Affiliations Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, CURE: Digestive Diseases Research Center, Los Angeles, California, United States of America

  ⨯
• James Sinnett-Smith,

  Roles Data curation, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, CURE: Digestive Diseases Research Center, Los Angeles, California, United States of America, VA Greater Los Angeles Health Care System, Los Angeles, California, United States of America

  ⨯
• Guido Eibl,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Validation, Writing – review & editing

  Affiliations Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, CURE: Digestive Diseases Research Center, Los Angeles, California, United States of America

  ⨯
• Enrique Rozengurt

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: erozengurt@mednet.ucla.edu

  Affiliations Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, CURE: Digestive Diseases Research Center, Los Angeles, California, United States of America, VA Greater Los Angeles Health Care System, Los Angeles, California, United States of America

  http://orcid.org/0000-0002-7838-9170

  ⨯