Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS

Odin Goovaerts; Marguerite Massinga-Loembé; Pascale Ondoa; Ann Ceulemans; William Worodria; Harriet Mayanja-Kizza; Robert Colebunders; Luc Kestens; for the TB-IRIS Study Group

doi:10.1371/journal.pone.0215991

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Open Access

Peer-reviewed

Research Article

Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS

Odin Goovaerts ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ogoovaerts@itg.be

Affiliation Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

http://orcid.org/0000-0002-4959-4677

⨯
Marguerite Massinga-Loembé,

Roles Project administration

Affiliations Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium, Centre de Recherches Médicales de Lambaréné (CERMEL), Albert Schweitzer Hospital, Lambarene, Gabon, Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany
⨯
Pascale Ondoa,

Roles Project administration

Affiliation Department of Global Health and Amsterdam Institute for Global Health and Development, Academic Medical Centre, Amsterdam, The Netherlands
⨯
Ann Ceulemans,

Roles Investigation, Methodology, Validation

Affiliation Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
⨯
William Worodria,

Roles Funding acquisition, Investigation, Project administration, Validation

Affiliations Department of Medicine, Mulago Hospital, Kampala, Uganda, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda, Infectious Diseases Network for Treatment and Research in Africa (INTERACT), Kampala, Uganda
⨯
Harriet Mayanja-Kizza,

Roles Project administration

Affiliations Department of Medicine, Mulago Hospital, Kampala, Uganda, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda
⨯
Robert Colebunders,

Roles Investigation, Project administration, Validation

Affiliation Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
⨯
Luc Kestens,

Roles Funding acquisition, Project administration, Supervision, Validation

Affiliation Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

http://orcid.org/0000-0001-9374-1921

⨯
for the TB-IRIS Study Group

¶Membership of the TB-IRIS Study Group is provided in the Acknowledgments.
⨯

Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS

Odin Goovaerts,
Marguerite Massinga-Loembé,
Pascale Ondoa,
Ann Ceulemans,
William Worodria,
Harriet Mayanja-Kizza,
Robert Colebunders,
Luc Kestens,
for the TB-IRIS Study Group

Published: April 25, 2019
https://doi.org/10.1371/journal.pone.0215991

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T cells
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Monocytes
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Lymphocytes
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Antiretroviral therapy
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NK cells
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