Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease

Xiaopei Zhou; Weimin Jia; Zhengyi Ni; Ali Wang; Zhenxing Liu; Meiqi Hou; Mi Zhou; Zhongwen Tang; Dazhi Zhang; Lei Li; Tiantian Han; Yang Tan; Geng Luo; Jiarui Wang; Yanling Wu; Xianqin Zhang

doi:10.1371/journal.pone.0215648

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Open Access

Peer-reviewed

Research Article

Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease

Xiaopei Zhou ,

Contributed equally to this work with: Xiaopei Zhou, Weimin Jia, Zhengyi Ni, Ali Wang, Zhenxing Liu

Roles Writing – original draft

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Weimin Jia ,

Contributed equally to this work with: Xiaopei Zhou, Weimin Jia, Zhengyi Ni, Ali Wang, Zhenxing Liu

Roles Data curation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Zhengyi Ni ,

Contributed equally to this work with: Xiaopei Zhou, Weimin Jia, Zhengyi Ni, Ali Wang, Zhenxing Liu

Roles Resources

Affiliation Wuhan Jinyintan Hospital, Wuhan, Hubei, China
⨯
Ali Wang ,

Contributed equally to this work with: Xiaopei Zhou, Weimin Jia, Zhengyi Ni, Ali Wang, Zhenxing Liu

Roles Data curation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Zhenxing Liu ,

Contributed equally to this work with: Xiaopei Zhou, Weimin Jia, Zhengyi Ni, Ali Wang, Zhenxing Liu

Roles Data curation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Meiqi Hou,

Roles Data curation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Mi Zhou,

Roles Resources

Affiliation Wuhan Jinyintan Hospital, Wuhan, Hubei, China
⨯
Zhongwen Tang,

Roles Resources

Affiliation Wuhan Jinyintan Hospital, Wuhan, Hubei, China
⨯
Dazhi Zhang,

Roles Data curation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Lei Li,

Roles Resources

Affiliation Wuhan Jinyintan Hospital, Wuhan, Hubei, China
⨯
Tiantian Han,

Roles Data curation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Yang Tan,

Roles Validation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Geng Luo,

Roles Validation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jiarui Wang,

Roles Validation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Yanling Wu,

Roles Validation

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
[ ... ],
Xianqin Zhang

Roles Writing – review & editing

* E-mail: xqzhang04@hust.edu.cn

Affiliation Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China

http://orcid.org/0000-0002-0103-2341

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Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease

Xiaopei Zhou,
Weimin Jia,
Zhengyi Ni,
Ali Wang,
Zhenxing Liu,
Meiqi Hou,
Mi Zhou,
Zhongwen Tang,
Dazhi Zhang,
Lei Li

Published: April 18, 2019
https://doi.org/10.1371/journal.pone.0215648

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