A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle

Laura B. A. Williams; Lindsay M. Fry; David R. Herndon; Valentina Franceschi; David A. Schneider; Gaetano Donofrio; Donald P. Knowles

doi:10.1371/journal.pone.0215605

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Open Access

Peer-reviewed

Research Article

A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle

Laura B. A. Williams ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft

* E-mail: lartz@wsu.edu

Affiliation Department of Veterinary Microbiology & Pathology, Washington State University, Pullman, Washington, United States of America

http://orcid.org/0000-0002-6229-4820

⨯
Lindsay M. Fry,

Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Visualization, Writing – review & editing

Affiliations Department of Veterinary Microbiology & Pathology, Washington State University, Pullman, Washington, United States of America, Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America
⨯
David R. Herndon,

Roles Data curation, Software

Affiliation Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America
⨯
Valentina Franceschi,

Roles Data curation

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯
David A. Schneider,

Roles Formal analysis, Software

Affiliation Animal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture, Pullman, Washington, United States of America
⨯
Gaetano Donofrio,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯
Donald P. Knowles

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – review & editing

Affiliation Department of Veterinary Microbiology & Pathology, Washington State University, Pullman, Washington, United States of America
⨯

A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle

Laura B. A. Williams,
Lindsay M. Fry,
David R. Herndon,
Valentina Franceschi,
David A. Schneider,
Gaetano Donofrio,
Donald P. Knowles

Published: April 19, 2019
https://doi.org/10.1371/journal.pone.0215605

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