Heavy-atom labeling of RNA by PLOR for de novo crystallographic phasing

Jason R. Stagno; Ping Yu; Marzena A. Dyba; Yun-Xing Wang; Yu Liu

doi:10.1371/journal.pone.0215555

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Open Access

Peer-reviewed

Research Article

Heavy-atom labeling of RNA by PLOR for de novo crystallographic phasing

Jason R. Stagno ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

* E-mail: jason.stagno@nih.gov (JRS); liuyu_sjtu@sjtu.edu.cn (YL)

Affiliation Protein-Nucleic Acid Interaction Section, Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America

http://orcid.org/0000-0002-6464-7829

⨯
Ping Yu,

Roles Investigation

Affiliation Protein-Nucleic Acid Interaction Section, Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
⨯
Marzena A. Dyba,

Roles Investigation, Methodology, Resources

Affiliation Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Yun-Xing Wang,

Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Protein-Nucleic Acid Interaction Section, Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
⨯
Yu Liu

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: jason.stagno@nih.gov (JRS); liuyu_sjtu@sjtu.edu.cn (YL)

Affiliations Protein-Nucleic Acid Interaction Section, Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China
⨯

Heavy-atom labeling of RNA by PLOR for de novo crystallographic phasing

Jason R. Stagno,
Ping Yu,
Marzena A. Dyba,
Yun-Xing Wang,
Yu Liu

Published: April 15, 2019
https://doi.org/10.1371/journal.pone.0215555

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RNA structure
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Crystal structure
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Crystal structure refinement
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Nucleotides
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