Estimating genome-wide off-target effects for pyrrole-imidazole polyamide binding by a pathway-based expression profiling approach

• Jason Lin ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: linjason@chiba-cc.jp (JL); hnagase@chiba-cc.jp (HN)

  Affiliations Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan, Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Koto-ku, Tokyo, Japan

  http://orcid.org/0000-0002-8086-3185

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• Sakthisri Krishnamurthy ,

  Contributed equally to this work with: Sakthisri Krishnamurthy, Hiroyuki Yoda

  Roles Data curation, Investigation

  Affiliation Laboratory of Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

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• Hiroyuki Yoda ,

  Contributed equally to this work with: Sakthisri Krishnamurthy, Hiroyuki Yoda

  Roles Data curation, Investigation

  Affiliation Laboratory of Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

  http://orcid.org/0000-0002-5528-8940

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• Yoshinao Shinozaki,

  Roles Investigation

  Affiliation Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

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• Takayoshi Watanabe,

  Roles Investigation

  Affiliation Laboratory of Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

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• Nobuko Koshikawa,

  Roles Resources, Supervision

  Affiliation Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

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• Atsushi Takatori,

  Roles Data curation, Funding acquisition, Investigation, Resources

  Affiliation Laboratory of Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

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• Paul Horton,

  Roles Resources, Supervision

  Affiliations Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan, Institute of Medical Informatics, National Cheng Kung University, Tainan, Taiwan

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• Hiroki Nagase

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: linjason@chiba-cc.jp (JL); hnagase@chiba-cc.jp (HN)

  Affiliation Laboratory of Cancer Genetics, Chiba Cancer Center Research Institute, Chuo-ku, Chiba, Japan

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