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Open Access
Peer-reviewed
Research Article
Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting
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Cheng Cheng ,
Contributed equally to this work with: Cheng Cheng, Kai Xu
Roles Investigation, Methodology, Project administration, Writing – original draft
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Kai Xu ,
Contributed equally to this work with: Cheng Cheng, Kai Xu
Roles Investigation, Methodology, Project administration, Writing – original draft
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Rui Kong,
Roles Investigation, Methodology, Project administration, Writing – original draft
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Gwo-Yu Chuang,
Roles Investigation, Methodology, Project administration, Writing – original draft
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Angela R. Corrigan,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Hui Geng,
Roles Resources
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Kurt R. Hill,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Alexander J. Jafari,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Sijy O’Dell,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Li Ou,
Roles Resources
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Reda Rawi,
Roles Methodology
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Ariana P. Rowshan,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Edward K. Sarfo,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Mallika Sastry,
Roles Resources
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Kevin O. Saunders,
Roles Resources
Affiliation Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America
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Stephen D. Schmidt,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Shuishu Wang,
Roles Writing – review & editing
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Winston Wu,
Roles Formal analysis
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Baoshan Zhang,
Roles Investigation
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Nicole A. Doria-Rose,
Roles Supervision, Writing – review & editing
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Barton F. Haynes,
Roles Resources, Supervision
Affiliation Duke Human Vaccine Institute, Duke School of Medicine, Durham, North Carolina, United States of America
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Diana G. Scorpio,
Roles Supervision
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Lawrence Shapiro,
Roles Supervision, Writing – original draft
Affiliations Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America
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John R. Mascola ,
Roles Supervision, Writing – review & editing
* E-mail: jmascola@nih.gov (JRM); pkwong@mail.nih.gov (PDK)
Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Peter D. Kwong
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: jmascola@nih.gov (JRM); pkwong@mail.nih.gov (PDK)
Affiliations Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America
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Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting
- Cheng Cheng,
- Kai Xu,
- Rui Kong,
- Gwo-Yu Chuang,
- Angela R. Corrigan,
- Hui Geng,
- Kurt R. Hill,
- Alexander J. Jafari,
- Sijy O’Dell,
- Li Ou
- Published: April 17, 2019
- https://doi.org/10.1371/journal.pone.0215163