Delivery of self-amplifying RNA vaccines in in vitro reconstituted virus-like particles

• Adam Biddlecome ,

  Contributed equally to this work with: Adam Biddlecome, Habtom H. Habte

  Roles Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, University of California, Los Angeles, California, United States of America

  ⨯
• Habtom H. Habte ,

  Contributed equally to this work with: Adam Biddlecome, Habtom H. Habte

  Roles Conceptualization, Investigation, Methodology, Project administration, Writing & review – editing

  Affiliation Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, United States of America

  ⨯
• Katherine M. McGrath,

  Roles Investigation, Methodology

  Affiliation Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, United States of America

  ⨯
• Sharmila Sambanthamoorthy,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, United States of America

  ⨯
• Melanie Wurm,

  Roles Conceptualization, Investigation, Methodology, Project administration, Visualization, Writing – review & editing

  Affiliation Boehringer-Ingelheim RCV GmbH & Co KG, Vienna, Austria

  ⨯
• Martina M. Sykora,

  Roles Investigation

  Affiliation Boehringer-Ingelheim RCV GmbH & Co KG, Vienna, Austria

  ⨯
• Charles M. Knobler,

  Roles Conceptualization, Formal analysis, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, University of California, Los Angeles, California, United States of America

  ⨯
• Ivo C. Lorenz,

  Roles Conceptualization, Methodology, Project administration, Writing – review & editing

  Affiliation Tri-Institutional Therapeutics Discovery Institute, New York, New York, United States of America

  http://orcid.org/0000-0002-7373-1176

  ⨯
• Marcio Lasaro,

  Roles Conceptualization, Project administration

  Affiliation Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, United States of America

  ⨯
• Knut Elbers ,

  Roles Conceptualization, Project administration, Supervision

  * E-mail: knut.elbers@boehringer-ingelheim.com (KE); gelbart@chem.ucla.edu (WMG)

  Affiliation Boehringer-Ingelheim Pharma GmbH & Co KG, Biberach, Germany

  ⨯
• William M. Gelbart

  Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: knut.elbers@boehringer-ingelheim.com (KE); gelbart@chem.ucla.edu (WMG)

  Affiliation Department of Chemistry and Biochemistry, University of California, Los Angeles, California, United States of America

  http://orcid.org/0000-0003-2125-4256

  ⨯